drugis.org

EUdraCT import available for testing

01 Apr 2019 — Daan Reid

We are pleased to announce that study import for ADDIS using EUdraCT XML format is available for testing on our test server. Please report any issues to info@drugis.org.

ADDIS 2 release 15

11 Mar 2019 — Daan Reid

We are proud to announce ADDIS 2 release 15. This release contains the following new features and improvements:

Added support for a structured Excel format for both export and import of studies and datasets. Its specification can be found here
Added support for data entry and analysis of several types of contrast data (e.g. hazard ratio, odds ratio).
Improvements to the benefit-risk analysis component, both the stand-alone MCDA component and the submodule of ADDIS:
- Added ‘Settings’ screen, letting users control the workspace and effects tables.
- Added support for multiple data sources for a single criterion.
- Added ‘Matching’ preference elicitation method.
- Users can now download the problem of a workspace as a JSON file on the overview tab.

The full list of changes can be found at the bottom of this post.

ADDIS
- Features
  - Created an Excel file format that allows import and export of studies and datasets to ADDIS.
  - Added support for study contrast data (data entry, network meta-analysis, benefit-risk analysis).
  - User interface improvements
    - Added loading indicators when the system is busy.
    - Front page: users list no longer goes off screen.
    - Study entry: increased input validation for measurements.
    - Study entry: warn users when there are duplicate concept mappings.
- Bugfixes
  - Restored missing error messages for network meta-analysis creation.
  - Enable editing dataset names.
  - D80-table fixes for unknown values and missing primary measurement
  - Fixed autocomplete for drugs and units in drug treatment creation.
  - Fixed breadcrumbs
  - Project report: links now check whether benefit-risk analyses are finalized.
  - Drug treatments now require at least one drug.
MCDA
- Features
  - Added ‘Settings’ screen, letting users control the workspace and effects table.
  - Settings added:
    - Effects table display modes:
      - ‘Effects’ - shows input as entered for effects, and the median/mode for distributions.
      - ‘Source data’ - Shows input as entered for effects, and the parameters for distributions.
      - ‘Deterministic MCDA’ - shows only effect point estimates, no confidence interval.
      - ‘SMAA’ - shows effects as calculated by SMAA, i.e. by sampling from their distributions.
    - Toggle between mode and median for the effects table SMAA display mode.
    - Toggle between between percentage and decimal display of dichotomous and cumulative probability effects.
  - Effects table improvements:
    - Allow hiding of non-alternative columns.
    - Added ‘Strength of evidence’ and ‘Uncertainty’ columns.
  - Preferences improvements:
    - Added a ‘willingness to trade off’ chart, letting the user explore the weight space via acceptability curves.
    - Changed Swing Weighting elicitation, now supporting direct weight setting, both precise and imprecise.
    - Added Matching preference elicitation method.
  - Added support for multiple data sources for a single criterion.
  - Added the ability to edit new copies of existing workspaces.
  - Let users change labels in several figures to help with overcrowded plots.
  - Support SSL certificate-based user authentication.
  - Users can now download the problem of a workspace as a JSON file on the overview tab.
  - Criteria and alternatives can now be reordered on the overview tab.
  - Uploaded JSON files are now checked for validity, showing a warning for invalid files.
  - Manual input improvements:
    - More input validation and error feedback.
    - Added support for NE (not estimable) values.
    - Added support for empty cells.
- Minor changes
  - Display unit of measurement during partial value function creation.
  - Changed the way criteria are displayed on the overview tab.
  - Manual input:
    - Favourability is now optional.
    - Values calculated from inputs are now being rounded.
    - Units, references, and description are now shown during data entry.
    - Allow reordering criteria and alternatives.
  - Toggling effects table columns is now workspace-wide.
  - Effects table descriptions are now always fully shown.
  - Moved weights table to deterministic analysis tab.
  - Ranking preference elicitation can now be cancelled.
  - Ask for scenario name on creation instead randomly generating one.
  - SMAA tab is now disabled if there is no uncertainty.
  - Allow changing of criterions’ favourability.
  - Show favourability in every effects table.
- Bugfixes
  - Manual input:
    - Only make references clickable if they are URLs.
    - While adding a criterion, the button now says ‘add’ instead of ‘edit’.
    - Clicking the normal distribution checkbox no longer closes the dropdown.
    - Refreshing the page no longer causes the table in step 2 to disappear.
    - It is no longer possible to enter 0% for a dichotomous effect.
    - Fix bug preventing criteria from being deleted
    - Input popup in step 2 no longer becomes very small if there are many alternatives.
  - Fixed math formula display in the manual.
  - Subproblem creation:
    - Fix several scale range errors.
    - Baseline alternatives can no longer be deselected after renaming them.
    - Theoretical scale ranges are now considered during creation.
  - Fix missing criterion name during partial value function creation.
  - Improve support for special characters in names.
  - Fix central weights table in case there’s no hits.
  - The default problem now has configured ranges.
All
- Features
  - Give each page a title, making browser history informative
  - Improve build process and stability using yarn and webpack.
  - Concatenate and minify javascript and html, decreasing page loading time.
- Minor changes
  - Added more contextual help icons, select better locations in the manual for help links.
  - Unify look of the manual across our web applications.
- Bugfixes
  - IE11 fixes:
    - sliders, modals and R results.
  - Various other bugfixes.

Probiotics article published

31 Jul 2018 — Daan Reid

We are pleased to announce that a journal article that used ADDIS was published in the Journal of Pediatric Gastroenterology and Nutrition.

We are pleased to announce that the follow-up to the GetReal project has launched, and that we are taking part in it. The new project will focus on promoting wider adoption of the findings of the first GetReal, and making the project’s outputs financially self-sustaining.

ADDIS 2 release 14

04 Dec 2017 — Daan Reid

We are proud to announce ADDIS 2 release 14. This release contains the following new features and improvements:

We have improved the benefit-risk analysis component, both the stand-alone MCDA component and the submodule of ADDIS:
- The manual entry process for the standalone component has been extended and streamlined.
- It is now possible to delete workspaces, and create new ones that are based on existing ones.
- Besides the SMAA analysis there is now also a deterministic analysis tab, allowing for sensitivity analysis.
- We have streamlined the problem definition process.
- We have added contextual help throughout the benefit-risk screens and have extended the manual to describe the new user interface.
- Graphs and tables now have export actions
We have added support for survival data throughout our applications.

To see the new features in action, watch the release video.

Our coming release will be at the end of March. The main focus will be getting data into and out of the system, both through file actions (e.g. MS Excel import, export) and improvements of the data entry module of ADDIS. We also expect to make further small improvements to the benefit-risk module.

News