ADDIS Release 1.2

Download ADDIS v1.2.1

Release history

Release 1.2.1

Release Date: 2010-10-21

ADDIS v1.2.1 is a bugfix release. There was an issue with the newly introduced single-study benefit-risk analysis that prevented any domain object from being deleted or edited. This has been fixed.

Release 1.2

Release Date: 2010-09-27

We are happy to announce the release of ADDIS (Aggregate Data Drug Information System) version 1.2. We deviate from our normal 3-monthly schedule to introduce an important feature: benefit-risk analysis based on a single study.

In single-study benefit-risk models, measurements are based on a Beta approximation of the binomial success probability (dichotomous outcomes) or on a Normal approximation of a continuous outcome. The single-study models are created using the same benefit-risk wizard that is used to construct benefit-risk models based on (network) meta-analyses. The advantage of single-study benefit-risk models is that all measurements are absolute, and thus that the measurement scales are easily interpreted. It is also not necessary to run any sub-analyses to inform the benefit-risk model. However, the SMAA simulation itself is a lot slower when Beta distributions are used.

This release also fixes an annoying bug that surfaced on Windows: switching the preferences from MISSING to ORDINAL didn't always work.

Getting ADDIS

Download ADDIS v1.2.1

Source code is also available: ADDIS v1.2.1 source tag

Running ADDIS

Extract the ZIP archive to a local directory. Then double-click the 'addis-1.2.1.jar' file. Now you should see the ADDIS welcome screen, where you can choose to load an example data set, load a file, or create a new data set. If you've never used ADDIS, we recommend that you take a look at the example data set.

If double-clicking the JAR file did not launch ADDIS, you are most likely lacking the Java run-time environment. You can get this from


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