News

MCDA web app updated

01 Nov 2013 — Gert van Valkenhoef

We have just updated our web based multiple criteria decision analysis (MCDA) preference elicitation tool. This component will be used in ADDIS 2.0 to support benefit-risk decisions. It is currently available online at mcda.clinici.co. The new features include:

  • Workspaces and scenarios: store the intermediate results of preference elicitation in your browser.
  • Overview: shows the elicited preference information in one place.
  • Exact SWING: preference elicitation leading to an exact weighting.
  • Extensive refactoring of the client-side code and many bugfixes on both the client and server side.

You will need a recent browser; we recommend Mozilla Firefox or Google Chrome. Several examples are provided. You can also load your own benefit-risk assessments by exporting them from ADDIS 1.16.4 or later. We would be glad to hear your feedback.


R packages updated

01 Nov 2013 — Gert van Valkenhoef
  • Version 0.5-1 of the GeMTC R package fixes several bugs and improves the behavior of plotting functions. See the gemtc NEWS file on CRAN for a full changelog.
  • Version 0.3 of the hitandrun R package adds the ability to deal with arbitrary linear equality constraints, in addition inequality constraints. See the hitandrun NEWS file on CRAN for a full changelog.
  • Version 0.2-1 of the smaa R package fixes two minor bugs and improves the performance of the ranking entropy calculation. See the smaa NEWS file on CRAN for a full changelog.

GeMTC R package updated

24 Sep 2013 — Gert van Valkenhoef

Version 0.5 of the GeMTC R package has several new features:

  • Support for node-splitting models
  • Model fit diagnostics: Deviance Information Criterion (JAGS only)
  • Better support for rank probabilities

For a full changelog, see the NEWS file on the GeMTC CRAN page.


ADDIS 1.16.5 bugfix release

20 Sep 2013 — Gert van Valkenhoef

ADDIS v1.16.5 fixes several minor bugs. Specifically, it fixes compatibility problems for Java 6 and makes ClinicalTrials.gov results import more robust to missing data.


Commissioned project results

03 Sep 2013 — Gert van Valkenhoef

The Escher commissioned project, "industry requirements and a data standard for ADDIS", has been completed and the results are available.

Hans van Leeuwen carried out interviews with industry stakeholders to evaluate ADDIS as a tool for benefit-risk analysis. An executive summary of the results is now available.

Jozef Aerts evaluated the ADDIS data model and improved various aspects of it to increase compatibility with existing industry standards (CDISC, BRIDG, etc.) and internal consistency of the data model. The resulting XML Schema, validation rules, and documentation are available for download: ADDIS - Standard for Exchange of Aggregated Data in Clinical Research - Specification Document version 1.0.