News

GeMTC R package 0.8

01 Mar 2016 — Gert van Valkenhoef

We are proud to announce version 0.8 of our R package for network meta-analysis, GeMTC.

This new version adds support for network meta-regression models and models where some evidence (e.g. observation data) is down-weighted. See GeMTC on CRAN for more information.


ADDIS 2 release 7

27 Nov 2015 — Daan Reid

We are proud to announce the seventh preview version of our web-based redevelopment of ADDIS, ADDIS 2 release 7. This release had several themes. First, we performed user testing for both GeMTC-web and Trialverse. Second, we expanded the network meta-analysis functionality of ADDIS, which is also available as a separate web-application at GeMTC-web. Third, we expanded the study management functionality of Trialverse with search and copying. Fourth, we addressed the most common concerns of our test users.

Release 7 contains the following new features:

  • GeMTC:
    • Inline help for all terminology, along with a brief user's manual.
    • Allow model run length extension.
    • Allow specification of heterogeneity prior.
    • An overview screen for nodesplitting analysis of inconsistency.
    • Several improvements to the user interface based on user feedback.
  • Trialverse:
    • Study search.
    • Allow copying of others' studies to own datasets.

The functionality developed in release 7 is showcased in these videos:

The focus of the next release will be divided between three subjects:

  • Further improvements to the evidence synthesis functionality, including the addition of network meta-regression models.
  • Improving the integration between the ADDIS and Trialverse components.
  • Further user testing of the evidence synthesis functionality.

ADDIS 2 release 6

21 Aug 2015 — Daan Reid

We are proud to announce the sixth preview version of our web-based redevelopment of ADDIS, ADDIS 2 release 6. The majority of this release was devoted to expanding the network meta-analysis functionality of ADDIS. We have also made this functionality available as a separate web-application at gemtc.drugis.org. Release 6 contains the following new features:

  • Support 3 types of meta-analysis (network, pairwise, node-splitting).
  • Allow setting of model parameters (fixed effect vs. random effects, likelihood/link function, run-length parameters).
  • More model results (convergence diagnostics, relative effects plots for network meta-analyses, study effect forest plot for pairwise meta-analyses).

The functionality developed in release 6 is showcased in this video.

The focus of the next release will be divided between three subjects:

  • Expanding Trialverse with features to include others' extractions, and laying groundwork for automating tasks.
  • Further expanding the NMA functionality, allowing inter-model comparisons, the specification of prior distributions, and the exporting of figures and data so they can be used in reports.
  • User testing to improve the usability and stability of the platform.

ADDIS 2 release 5

15 May 2015 — Daan Reid

We are proud to announce the fifth preview version of our web-based redevelopment of ADDIS, ADDIS 2 release 5. The majority of this release was devoted to the Trialverse component, which is intended to be the portal where users extract and share clinical trials data. With this release, we will freeze Trialverse development (besides bugfixes) for the near future. Release 5 contains the following new features:

  • Creation of complete studies (general information, design, results)
  • Creation of dataset-level concepts (variables, drugs) and their mapping to study-level concepts
  • Versioning of datasets (all changes are tracked, previous versions always visible)
  • Updated the MCDA component to the latest version

The functionality developed in release 5 is showcased in this video. The next release will focus on expanding the analysis functionality of ADDIS 2, particularly the network meta-analysis component.


mcda.drugis.org updated

05 May 2015 — Gert van Valkenhoef

We are proud to announce the release of a new version of our web-based Multiple Criteria Decision Analysis (MCDA) tool. The majority of this release was devoted to polishing the user interface, and introducing a new way of eliciting Partial Value Functions. We invite everyone to try it out at mcda.drugis.org.

The release contains the following features and bug fixes:

  • Remove the MacBeth Partial Value Function elicitation, in favor of a method based on bisection
  • Add clear warnings when information will be destroyed
  • Add a legend to the heat maps
  • Report units of measurement more consistently, and display unbounded intervals correctly
  • Add Gravatar support (profile pictures)
  • Considerably improve client-side performance

Thanks to Joël Kuiper and Douwe Postmus for their work on this release, and the IMI PROTECT project for their support.